Youtube Favorite: Van Horn, Texas to Guadalupe Mountains National Park
From YouTube:
Texas 54 exits tiny Van Horn, heading north. The road gives you a great look at El Capitan and Guadalupe Peak for about a half hour before finally turning onto US 62/180 for the final few miles into Guadalupe Mountains National Park. Serious road geeks will also notice that this video begins at the western terminus of US Highway 90, which finishes its cross-country journey at Van Horn.